Cerebral hypoxia

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Cerebral hypoxia refers to deprivation of oxygen supply to brain tissue. Mild or moderate cerebral hypoxia is sometimes known as diffuse cerebral hypoxia. It can cause confusion and fainting, but its effects are reversible. Total deprivation of oxygen to the brain is called cerebral anoxia. Extended periods of cerebral hypoxia can lead to brain death or permanent brain damage.

Most cases of cerebral hypoxia are caused by a sudden change in brain oxygen levels. The body can normally respond to mild gradual changes in blood oxygen with little or no noticeable effect on brain function. The acclimatization process used by high altitude climbers is an example of such adjustment.

The presence of cerebral hypoxia symptoms indicates that the brain has been overwhelmed by a change in its oxygen supply. Consequently, even mild symptoms of cerebral hypoxia require immediate medical attention.

Cerebral hypoxia is typically grouped into four categories depending on the severity and location of the brain’s oxygen deprivation:[1]

Cerebral hypoxia can also be classified by the cause of the reduced brain oxygen:[2]

Cerebral hypoxia can be caused by any event that severely interferes with the brain’s ability to receive or process oxygen. This event may be internal or external to the body.

Mild and moderate forms of cerebral hypoxia may be caused by various diseases that interfere with breathing and blood oxygenation. Severe asthma and various sorts of anemia can cause some degree of diffuse cerebral hypoxia. Other causes include work in nitrogen rich environments, ascent from a deep water dive, flying at high altitudes in an un-pressurized cabin, and intense exercise at high altitudes prior to acclimatization.

Severe cerebral hypoxia and anoxia is usually caused by traumatic events. Examples include choking, drowning, strangulation, smoke inhalation, drug overdoses, crushing of the trachea, status asthmaticus, and shock.[4]

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