Mallory-Weiss syndrome



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Mallory-Weiss syndrome refers to bleeding from tears (a Mallory-Weiss tear) in the mucosa at the junction of the stomach and esophagus, usually caused by severe retching, coughing, or vomiting.

It is often associated with alcoholism[1] and eating disorders and there is some evidence that presence of a hiatal hernia is a predisposing condition.

Mallory-Weiss syndrome often presents as an episode of vomiting up blood (hematemesis) after violent retching or vomiting, but may also be noticed as old blood in the stool (melena), and a history of retching may be absent.

In most cases, the bleeding stops spontaneously after 24-48 hours, but endoscopic or surgical treatment is sometimes required and rarely the condition is fatal.

Definitive diagnosis is by endoscopy.

Treatment is usually supportive as persistent bleeding is uncommon. However cauterization or injection of epinephrine[2] to stop the bleeding may be undertaken during the index endoscopy procedure.

USMLE ALGORITHMS: Upper GI Bleeding
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This Video Algorithm is going to discuss Upper GI Bleeding. Topics included: - M...

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